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Chromatography

HPLC and SFC are versatile chromatographic methods for purification and analysis. Our Kromasil® stationary phases have you covered for your most demanding needs.

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Selecting the right chromatographic media for your applications is the key to successful separations and purifications.

Versatile chromatographic methods for purification and analysis.

We develop outstanding silica-based stationary phases for process-scale high performance liquid chromatography (HPLC) and supercritical fluid chromatography (SFC) applications. 

 Kromasil® packing materials have built their reputation by improving efficiency and decreasing costs in your downstream purification step. This is possible because of the very strong, perfectly spherical, and totally porous silica particles derivatized with various surface chemistries. Those properties allow for maximum loadability of product to purify and a long stationary phase lifetime. 

Kromasil® media are also available in slurry-packed columns for development purposes and analytical applications down to UHPLC (ultra-high performance liquid chromatography). 

Please find more details on kromasil.com.

Featured products

Kromasil chromatography media

Kromasil 100-10-diC4

[M10DCblk] High performance spherical silica for analytical to process-scale liquid chromatography.(HPLC). Totally porous silica in 10 µm particle size and 100 Å pore size. Functionalized with a difunctional butyl silane. Available in bulk and in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil 100-10-C18

[M10CLblk] High performance spherical silica for analytical to process-scale liquid chromatography.(HPLC). Totally porous silica in 10 µm particle size and 100 Å pore size. Functionalized with a monofunctional octadecyl silane and end-capped. Available in bulk and in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil 100-10-C18(w)

[M10WLblk] High performance spherical silica for analytical to process-scale liquid chromatography.(HPLC). Totally porous silica in 10 µm particle size and 100 Å pore size. Available in bulk and in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil 100-13-C8

[M13CMblk] High performance spherical silica for analytical to process-scale liquid chromatography.(HPLC). Totally porous silica in 13 µm particle size and 100 Å pore size. Functionalized with a monofunctional octyl silane and end-capped. Available in bulk and in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil EternityXT-10-C18

[X10CLblk] High performance spherical silica for analytical to process-scale liquid chromatography.(HPLC). Totally porous silica in 10 µm particle size and 100 Å pore size and a reinforced organosilane surface for enhanced stability. Functionalized with a monofunctional octadecyl silane and end-capped. Available in bulk and in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil EternityXT-10-C8

[X10CMblk] High performance spherical silica for analytical to process-scale liquid chromatography.(HPLC). Totally porous silica in 10 µm particle size and 100 Å pore size and a reinforced organosilane surface for enhanced stability. Functionalized with a monofunctional octyl silane and end-capped. Available in bulk and in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil SFC-2.5-XT

[FH2XTblk] High performance spherical silica for analytical supercritical fluid chromatography.(SFC). Totally porous silica in 2.5 µm particle size and 100 Å pore size. Functionalized with an organo-silane surface. Only available in slurry-packed stainless steel columns.

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Kromasil chromatography media

Kromasil SFC-5-2EP

[F05EPblk] High performance spherical silica for analytical supercritical fluid chromatography.(SFC). Totally porous silica in 5 µm particle size and 100 Å pore size. Only available in slurry-packed stainless steel columns.

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Feature stories

Young female surfer riding the wave

Kromasil® wettable phase

An HPLC phase that has been specifically designed for polar compounds. This Kromasil® 100 Å C18(w) stationary phase permits loading and run start in 100% aqueous, enabling new opportunities for engineers and scientists working with HPLC. Read more on our dedicated Kromasil® chromatography media and columns website.
Young woman with insulin control patch on arm, out for a run listening to music

Insulin - a life-saving discovery

One important factor for the efficacy of insulin in medication, is that it needs to be pure, to allow for diabetics to use it every day for their entire lives.
A man and a women going for a mountain hike. Type 2 diabetes patients rely on their medicine to be able lead a healthy life. This is where Nouryon’s high-performing Kromasil chromatography solutions now support the pharmaceutical industry.

Efficient purification strategy for pharmaceuticals

Many of the substances used in the production of type 2 diabetes pharmaceuticals are challenging to purify. This is where our high-performing Kromasil® chromatography solutions now support the pharmaceutical industry.
two couples of winter hikers with pack and skis passing over endless snowy hills on a cristal-clear sunny day

When two are better than one

Kromasil® diC4 - now in 100 Å pore size to optimize the purification of GLP-1 agonist peptides

News release on kromasil.com Kromasil 100-10-diC4

Get in touch

For more information about our Kromasil® chromatography media, please contact our experts. We look forward to hearing from you.

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Kromasil® is a registered trademark of Nouryon in several countries worldwide.

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